Breathlessness and opioids

We've recently published a paper on how opioids can modulate breathlessness. (The whole manuscript is open access here). Low-dose opioids can be used for treating chronic breathlessness, but we don't know exactly how they work. Opioid receptors exist across the brain. These are part of the internal opioid system (endogenous opioid system) for natural pain relief. When … Continue reading Breathlessness and opioids

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Breathlessness & the Brain

Breathlessness can be many things. For example, it can be the shortness of breath after exercise - short-lived and laced with endorphins - or it can be the frightening gasping for breath experienced by patients with a range of diseases from cardiac failure and cancer to respiratory disease. From a physiological point of view, these may look quite … Continue reading Breathlessness & the Brain