Pulmonary rehab: changing the signal

Pulmonary rehabilitation is one of the most effective treatments for breathlessness in chronic obstructive pulmonary disease (COPD), yet its effect is variable. While up to 60% of patients who complete a course of treatment see an improvement, that leaves 40% that do not. Understanding why it works for some and not for others can help … Continue reading Pulmonary rehab: changing the signal

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MRI and motion correction

Magnetic resonance imaging is sensitive to motion. Just like with other images, movement may cause blurring and distortion ('artefacts'). To counteract this, motion correction methods are often used. These include devices that track motion as well as software that can correct some of the artefacts after the images have been collected. We have just published … Continue reading MRI and motion correction

Breathlessness and opioids

We've recently published a paper on how opioids can modulate breathlessness. (The whole manuscript is open access here). Low-dose opioids can be used for treating chronic breathlessness, but we don't know exactly how they work. Opioid receptors exist across the brain. These are part of the internal opioid system (endogenous opioid system) for natural pain relief. When … Continue reading Breathlessness and opioids

Predicting trouble: EEG, NO and stroke

We've recently published a paper titled "Electroencephalographic Response to Sodium Nitrite May Predict Delayed Cerebral Ischemia After Severe Subarachnoid Hemorrhage" on how electroencephalography (EEG for short) can be used to figure out which patients with a certain type of stroke (subarachnoid hemorrhage) will develop a complication after the initial brain bleed and which will not. … Continue reading Predicting trouble: EEG, NO and stroke